Coexistence of Ammonium Transporter and Channel Mechanisms in Amt-Mep-Rh Twin-His Variants Impairs the Filamentation Signaling Capacity of Fungal Mep2 Transceptors-Reference-Cited by-同舟云学术

Coexistence of Ammonium Transporter and Channel Mechanisms in Amt-Mep-Rh Twin-His Variants Impairs the Filamentation Signaling Capacity of Fungal Mep2 Transceptors

Published:2022-04-26 Issue:2 Volume:13 Page:
ISSN:2150-7511
Container-title:mBio
language:en
Short-container-title:mBio

Author:

Williamson Gordon¹,Brito Ana Sofia²,Bizior Adriana¹,Tamburrino Giulia³,Dias Mirandela Gaëtan¹²,Harris Thomas¹,Hoskisson Paul A.¹^ORCID,Zachariae Ulrich³,Marini Anna Maria²,Boeckstaens Mélanie²,Javelle Arnaud¹^ORCID

Affiliation:

1. Strathclyde Institute of Pharmacy and Biomedical Sciences, University of Strathclyde, Glasgow, United Kingdom

2. Biology of Membrane Transport Laboratory, Department of Molecular Biology, Université Libre de Bruxelles, Gosselies, Belgium

3. Computational Biology, School of Life Sciences, University of Dundee, Dundee, United Kingdom

Abstract

Fungal infections represent a significant threat to human health and cause huge damage to crop yields worldwide. The dimorphic switch between yeast and filamentous growth is associated with the virulence of pathogenic fungi.

Funder

tenovus scotland

UKRI | Natural Environment Research Council

Publisher

American Society for Microbiology

Subject

Virology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/mbio.02913-21

Reference54 articles.

1. Evolutionary conservation and diversification of Rh family genes and proteins

2. The MEP2 ammonium permease regulates pseudohyphal differentiation in Saccharomyces cerevisiae