Impact of Target Turnover on the Translation of Drug-Target Residence Time to Time-Dependent Antibacterial Activity-Reference-Cited by-同舟云学术

Impact of Target Turnover on the Translation of Drug-Target Residence Time to Time-Dependent Antibacterial Activity

Published:2021-08-06 Issue:9 Volume:7 Page:2755-2763
ISSN:2373-8227
Container-title:ACS Infectious Diseases
language:en
Short-container-title:ACS Infect. Dis.

Author:

Basu Rajeswari¹²,Wang Nan¹²,Basak Sneha¹²,Daryaee Fereidoon¹²,Babar Mustufa²,Allen Eleanor K.²,Walker Stephen G.³,Haley John D.⁴,Tonge Peter J.¹²⁵^ORCID

Affiliation:

1. Center for Advanced Study of Drug Action, Stony Brook University, John S. Toll Drive, Stony Brook, New York 11794-3400, United States

2. Department of Chemistry, Stony Brook University, John S. Toll Drive, Stony Brook, New York 11794-3400, United States

3. Department of Oral Biology and Pathology, Stony Brook University, John S. Toll Drive, Stony Brook, New York 11794-3400, United States

4. Department of Pathology, Stony Brook University, John S. Toll Drive, Stony Brook, New York 11794-3400, United States

5. Department of Radiology, Stony Brook University, John S. Toll Drive, Stony Brook, New York 11794-3400, United States

Funder

National Institute of General Medical Sciences

Publisher

American Chemical Society (ACS)

Subject

Infectious Diseases

Link

https://pubs.acs.org/doi/pdf/10.1021/acsinfecdis.1c00317

Reference47 articles.

1. Drugs for bad bugs: confronting the challenges of antibacterial discovery

2. Challenges of Antibacterial Discovery

3. ESKAPEing the labyrinth of antibacterial discovery

4. Delineating Bacteriostatic and Bactericidal Targets in Mycobacteria Using IPTG Inducible Antisense Expression

5. Genetic and chemical knockdown: a complementary strategy for evaluating an anti-infective target

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