Synthesis of Fused Bicyclic Piperidines: Potential Bioactive Templates for Medicinal Chemistry-Reference-Cited by-同舟云学术

Synthesis of Fused Bicyclic Piperidines: Potential Bioactive Templates for Medicinal Chemistry

Published:2014-11-26 Issue:1 Volume:80 Page:70-79
ISSN:0022-3263
Container-title:The Journal of Organic Chemistry
language:en
Short-container-title:J. Org. Chem.

Author:

Zhou Jinglan¹,Campbell-Conroy Erica L.¹,Silina Alina¹,Uy Johnny¹,Pierre Fabrice¹,Hurley Dennis J.¹,Hilgraf Nicole¹,Frieman Bryan A.¹,DeNinno Michael P.¹

Affiliation:

1. Department of Chemistry, Vertex Pharmaceuticals, Inc., 11010 Torreyana Road, San Diego, California 92121, United States

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/jo501967m

Reference35 articles.

1. A Comparison of Physiochemical Property Profiles of Development and Marketed Oral Drugs

2. What Do Medicinal Chemists Actually Make? A 50-Year Retrospective

3. Escape from Flatland: Increasing Saturation as an Approach to Improving Clinical Success

4. The impact of aromatic ring count on compound developability – are too many aromatic rings a liability in drug design?

5. Improving Drug Candidates by Design: A Focus on Physicochemical Properties As a Means of Improving Compound Disposition and Safety

Cited by 19 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. 2,5-disubstituted bicyclo[2.1.1]hexanes as rigidified cyclopentane variants;Chemical Science;2023

2. Copper-Catalyzed Nitrogen Atom Transfer to Isoquinolines via C–N Triple Bond Cleavage and Three-Component Cyclization;Organic Letters;2022-08-04

3. Access to Highly Strained Tricyclic Ketals Derived from Coumarins;The Journal of Organic Chemistry;2022-03-08

4. Silver‐Catalyzed Cross Dehydrogenative Coupling between Heteroarenes and Cyclic Ethers under Mild Conditions;ChemistrySelect;2021-03-18

5. The preparation and properties of 1,1-difluorocyclopropane derivatives;Beilstein Journal of Organic Chemistry;2021-01-26