Improving Drug Candidates by Design: A Focus on Physicochemical Properties As a Means of Improving Compound Disposition and Safety
Author:
Affiliation:
1. Department of Medicinal Chemistry, Bristol Myers Squibb Research and Development, 5 Research Parkway, Wallingford, Connecticut 06492, United States
Publisher
American Chemical Society (ACS)
Subject
Toxicology,General Medicine
Link
https://pubs.acs.org/doi/pdf/10.1021/tx200211v
Reference105 articles.
1. Can the pharmaceutical industry reduce attrition rates?
2. Pharmaceutical Research and Manufacturers of America, Chart Pack, available athttp://www.phrma.org/sites/default/files/159/phrma_chart_pack.pdf.
3. Pharmaceutical Research and Manufacturers of America, Pharmaceutical Industry Profile 2011 (Washington, DC: PhRMA, March 2011) available athttp://www.phrma.org/sites/default/files/159/phrma_profile_2011_final.pdf.
4. Drugs, leads, and drug-likeness: an analysis of some recently launched drugs
5. A Comparison of Physiochemical Property Profiles of Development and Marketed Oral Drugs
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