Access to Highly Strained Tricyclic Ketals Derived from Coumarins-Reference-Cited by-同舟云学术

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Access to Highly Strained Tricyclic Ketals Derived from Coumarins

Published:2022-03-08 Issue:6 Volume:87 Page:4476-4482
ISSN:0022-3263
Container-title:The Journal of Organic Chemistry
language:en
Short-container-title:J. Org. Chem.

Author:

Jonnalagadda Sravan K.¹,Huwaimel Bader I.¹²,Jonnalagadda Shirisha¹,Garrison Jered C.¹³^ORCID,Trippier Paul C.¹³⁴^ORCID

Affiliation:

1. Department of Pharmaceutical Sciences, College of Pharmacy, University of Nebraska Medical Center, Omaha, Nebraska 68106, United States

2. Department of Pharmaceutical Chemistry, College of Pharmacy, University of Hail, Hail, 81442, Kingdom of Saudi Arabia

3. Fred & Pamela Buffett Cancer Center, University of Nebraska Medical Center, Omaha, Nebraska 68106, United States

4. UNMC Center for Drug Discovery, University of Nebraska Medical Center, Omaha, Nebraska 68106, United States

Funder

National Cancer Institute

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.joc.2c00018

Reference29 articles.

1. Escape from Flatland: Increasing Saturation as an Approach to Improving Clinical Success

2. Fsp3: A new parameter for drug-likeness

3. On the origins of three-dimensionality in drug-like molecules

4. Synthesis of Fused Bicyclic Piperidines: Potential Bioactive Templates for Medicinal Chemistry

5. Escaping from Flatland: Antimalarial Activity of sp3-Rich Bridged Pyrrolidine Derivatives

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1. Catalytic Intramolecular Ketone Haloacylation Enabled Stereoselective Heterolytic Cleavage of Cyclopropyl Ketones with Enhanced Reactivity and Regioselectivity beyond Electronics;Organic Letters;2024-05-08

2. Aldo-Keto Reductase 1C3 Inhibitor Prodrug Improves Pharmacokinetic Profile and Demonstrates In Vivo Efficacy in a Prostate Cancer Xenograft Model;Journal of Medicinal Chemistry;2023-07-10

3. Asymmetric Radical Bicyclization for Stereoselective Construction of Tricyclic Chromanones and Chromanes with Fused Cyclopropanes;Journal of the American Chemical Society;2023-05-02

4. Selective carbonic anhydrase IX and XII inhibitors based around a functionalized coumarin scaffold;Drug Development Research;2023-03-05

5. A Ru(ii)-catalyzed C–H activation and annulation cascade for the construction of highly coumarin-fused benzo[a]quinolizin-4-ones and pyridin-2-ones;Organic Chemistry Frontiers;2023

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