Cytotoxicity and antioxidant activity of goldenberry extracts obtained with high intensity ultrasound

Author:

Codevilla Cristiane Franco1,Tischer Bruna1,Gindri Amanda Leitão1,Nogueira-Librelotto Daniele Rubert1,Barin Juliano Smanioto1,Silva Cristiane de Bona da1,Rolim Clarice Madalena Bueno1,Zepka Leila Queiroz1,Menezes Cristiano Ragagnin de1

Affiliation:

1. Universidade Federal de Santa Maria, Brazil

Abstract

ABSTRACT: The high intensity ultrasound-assisted extraction (HIU) is one of the most simple, quick and efficient techniques for the extraction of phenolic and other antioxidant compounds from plants. This is the first application of HIU for the extraction of these compounds from goldenberry fruit. The HIU and conventional extraction techniques showed similar results regarding to phenolic compounds and antioxidant capacity. However, the time required for HIU extraction (5min) was 24 times lower than conventional extraction (120min). Phenolic compounds reported were chlorogenic acid, caffeic acid and rutin. In vitro cytotoxicity assays were used for evaluation of extracts and the results showed that in a wide range of concentration, the extract maintains cell viability, thus indicating the possibility to use it as food with safety.

Publisher

FapUNIFESP (SciELO)

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