Efficacy of Flecainide in Catecholaminergic Polymorphic Ventricular Tachycardia Is Mutation-Independent but Reduced by Calcium Overload-Reference-Cited by-同舟云学术

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Efficacy of Flecainide in Catecholaminergic Polymorphic Ventricular Tachycardia Is Mutation-Independent but Reduced by Calcium Overload

Published:2019-08-13 Issue: Volume:10 Page:
ISSN:1664-042X
Container-title:Frontiers in Physiology
language:
Short-container-title:Front. Physiol.

Author:

Hwang Hyun Seok,Baldo Marcelo P.,Rodriguez Jose Pindado,Faggioni Michela,Knollmann Bjorn C.

Funder

National Heart, Lung, and Blood Institute

Publisher

Frontiers Media SA

Subject

Physiology (medical),Physiology

Reference34 articles.

1. The mechanism of flecainide action in CPVT does not involve a direct effect on RyR2.;Bannister;Circ. Res.,2015

2. Unnatural verticilide enantiomer inhibits type 2 ryanodine receptor-mediated calcium leak and is antiarrhythmic.;Batiste;Proc. Natl. Acad. Sci. U.S.A.,2019

3. Efficacy of flecainide in a patient with catecholaminergic polymorphic ventricular tachycardia.;Biernacka;Europace,2011

4. Bidirectional ventricular tachycardia and fibrillation elicited in a knock-in mouse model carrier of a mutation in the cardiac ryanodine receptor.;Cerrone;Circ. Res.,2005

5. Ablation of triadin causes loss of cardiac Ca2+ release units, impaired excitation-contraction coupling, and cardiac arrhythmias.;Chopra;Proc. Natl. Acad. Sci. U.S.A.,2009

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2. Insights on the mechanism of flecainide in catecholaminergic polymorphic ventricular tachycardia;Journal of Medicine and Life;2023-08

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5. How does flecainide impact RyR2 channel function?;Journal of General Physiology;2022-06-17

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