Insights on the mechanism of flecainide in catecholaminergic polymorphic ventricular tachycardia
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S.C. JURNALUL PENTRU MEDICINA SI VIATA S.R.L
Reference9 articles.
1. Evaluation of gene validity for CPVT and short QT syndrome in sudden arrhythmic death;Walsh R Adler A Amin AS Abiusi E;Eur Heart J,2022
2. Flecainide inhibits arrhythmogenic Ca2+ waves by open state block of ryanodine receptor Ca2+ release channels and reduction of Ca2+ spark mass;Hilliard FA Steele DS Laver D Yang Z;J Mol Cell Cardiol,2010
3. RYR2 Channel Inhibition Is the Principal Mechanism of Flecainide Action in CPVT;Kryshtal DO Blackwell DJ Egly CL Smith AN;Circ Res,2021
4. Short communication: flecainide exerts an antiarrhythmic effect in a mouse model of catecholaminergic polymorphic ventricular tachycardia by increasing the threshold for triggered activity;Liu N Denegri M Ruan Y Avelino-Cruz JE;Circ Res,2011
5. Flecainide reduces Ca(2+) spark and wave frequency via inhibition of the sarcolemmal sodium current;Sikkel MB Collins TP Rowlands C Shah M;Cardiovasc Res,2013
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