Inhibition of NF-kB/DNA Interactions and HIV-1 LTR Directed Transcription by Hybrid Molecules Containing Pyrrolo [2,1-c] [1,4] Benzodiazepine (PBD) and Oligopyrrole Carriers
Author:
Publisher
Wiley
Subject
Drug Discovery
Reference27 articles.
1. Structure and Synthesis of Distamycin A
2. Design, synthesis and biological activity of a pyrrolo [2,1-c][1,4]benzodiazepine (PBD)-distamycin hybrid
3. Synthesis, in Vitro Antiproliferative Activity, and DNA-Binding Properties of Hybrid Molecules Containing Pyrrolo[2,1-c][1,4]benzodiazepine and Minor-Groove-Binding Oligopyrrole Carriers
4. [2,1-c] [1,4]Benzodiazepine (PBD)-Distamycin Hybrid Inhibits DNA Binding to Transcription Factor Sp1
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1. Effects of Systematic Shortening of Noncovalent C8 Side Chain on the Cytotoxicity and NF-κB Inhibitory Capacity of Pyrrolobenzodiazepines (PBDs);Journal of Medicinal Chemistry;2019-01-28
2. Synthetic Strategies toward Bioactive Compounds for Chemotherapy: From Natural Products to Hybrid Strategy;KAGAKU TO SEIBUTSU;2017-06-20
3. GC-Targeted C8-Linked Pyrrolobenzodiazepine–Biaryl Conjugates with Femtomolar in Vitro Cytotoxicity and in Vivo Antitumor Activity in Mouse Models;Journal of Medicinal Chemistry;2013-03-21
4. Hybrid molecules between distamycin A and active moieties of antitumor agents;Bioorganic & Medicinal Chemistry;2007-01
5. Design, Synthesis, and Biophysical and Biological Evaluation of a Series of Pyrrolobenzodiazepine−Poly(N-methylpyrrole) Conjugates;Journal of Medicinal Chemistry;2006-08-05
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