Synthesis, in Vitro Antiproliferative Activity, and DNA-Binding Properties of Hybrid Molecules Containing Pyrrolo[2,1-c][1,4]benzodiazepine and Minor-Groove-Binding Oligopyrrole Carriers-Reference-Cited by-同舟云学术

Synthesis, in Vitro Antiproliferative Activity, and DNA-Binding Properties of Hybrid Molecules Containing Pyrrolo[2,1-c][1,4]benzodiazepine and Minor-Groove-Binding Oligopyrrole Carriers

Published:1999-11-30 Issue:25 Volume:42 Page:5131-5141
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Baraldi Pier Giovanni¹,Balboni Gianfranco¹,Cacciari Barbara¹,Guiotto Andrea¹,Manfredini Stefano¹,Romagnoli Romeo¹,Spalluto Giampiero¹,Thurston David E.¹,Howard Philip W.¹,Bianchi Nicoletta¹,Rutigliano Cristina¹,Mischiati Carlo¹,Gambari Roberto¹

Affiliation:

1. Dipartimento di Scienze Farmaceutiche e Dipartimento di Biochimica e Biologia Molecolare, Università di Ferrara, 44100 Ferrara, Italy, and CRC Gene Targeted Drug Design Research Group, School of Pharmacy and Biomedical Science, University of Portsmouth, St. Michael's Building, White Swan Road, Portsmouth, Hampshire PO1 2DT, United Kingdom

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm991033w

Reference38 articles.

1. Structure and Synthesis of Distamycin A

2. Structural modeling of the distamycin A-d(CGCGAATTCGCG)2 complex using 2D NMR and molecular mechanics

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