Evaluation of the Aryl Hydrocarbon Receptor Response in LMH 3D Spheroids
Author:
Affiliation:
1. National Wildlife Research CentreEnvironment and Climate Change CanadaOttawa Ontario Canada
2. Centre for Advanced Research in Environmental Genomics, Department of BiologyUniversity of OttawaOttawa Ontario Canada
Funder
Environment and Climate Change Canada
Publisher
Wiley
Subject
Health, Toxicology and Mutagenesis,Environmental Chemistry
Link
https://onlinelibrary.wiley.com/doi/pdf/10.1002/etc.4783
Reference48 articles.
1. Comparison of Hepatic 2D Sandwich Cultures and 3D Spheroids for Long-term Toxicity Applications: A Multicenter Study
2. Characterization of primary human hepatocyte spheroids as a model system for drug-induced liver injury, liver function and disease
3. Rat hepatocyte spheroids formed by rocked technique maintain differentiated hepatocyte gene expression and function
4. Hepatocyte cell lines: their use, scope and limitations in drug metabolism studies
5. Molecular mechanisms underlying the enhanced functions of three-dimensional hepatocyte aggregates
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