Concentration‐ and time‐dependent induction of Cyp1a and DNA damage response by benzo(a)pyrene in LMH three‐dimensional spheroids
Author:
Affiliation:
1. Environment and Climate Change Canada, National Wildlife Research Centre Ottawa Ontario Canada
2. Department of Biology University of Ottawa Ottawa Ontario Canada
Funder
Environment and Climate Change Canada
Publisher
Wiley
Subject
Health, Toxicology and Mutagenesis,Genetics(clinical),Epidemiology
Link
https://onlinelibrary.wiley.com/doi/pdf/10.1002/em.22433
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1. Integration of metabolic activation with a predictive toxicogenomics signature to classify genotoxic versus nongenotoxic chemicals in human TK 6 cells
2. ATM Phosphorylates Histone H2AX in Response to DNA Double-strand Breaks
3. Adaptive upregulation of DNA repair genes following benzo(a)pyrene diol epoxide protects against cell death at the expense of mutations
4. Three-Dimensional Cell Culture Systems and Their Applications in Drug Discovery and Cell-Based Biosensors
5. A Review of Three-Dimensional In Vitro Tissue Models for Drug Discovery and Transport Studies
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1. Benzo[a]pyrene-induced up-regulation of circ_0003552 via ALKBH5-mediated m6A modification promotes DNA damage in human bronchial epithelial cells;Environmental Pollution;2023-11
2. The Role of the Kynurenine/AhR Pathway in Diseases Related to Metabolism and Cancer;International Journal of Tryptophan Research;2023-01
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