Overview on legislation and scientific approaches for risk assessment of combined exposure to multiple chemicals: the potential EuroMix contribution

Author:

Rotter S.1,Beronius A.2,Boobis A. R.3,Hanberg A.2,van Klaveren J.4,Luijten M.5,Machera K.6,Nikolopoulou D.6,van der Voet H.7,Zilliacus J.2,Solecki R.1

Affiliation:

1. Department of Pesticides Safety, German Federal Institute for Risk Assessment - BfR, Berlin, Germany;

2. Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden;

3. Department of Medicine, Imperial College London, London, UK;

4. Centre for Nutrition, Prevention and Health Services, National Institute for Public Health and the Environment (RIVM), Bilthoven, The Netherlands;

5. Centre for Health Protection, National Institute for Public Health and the Environment (RIVM), Bilthoven, The Netherlands;

6. Laboratory of Pesticides Toxicology, Benaki Phytopathological Institute, Athens, Greece;

7. Biometris, Wageningen University & Research, Wageningen, The Netherlands

Funder

European Commission, H2020

Publisher

Informa UK Limited

Subject

Toxicology

Reference71 articles.

1. Altenburger R, Barouki R, Bergman Å, Brack W, Drakvik E, van Klaveren J, Kolossa-Gehring M. 2018. Position Paper: preventing risks for people and environment from hazardous chemical mixtures. [accessed 2018 October 16]. http://edcmixrisk.ki.se/wp-content/uploads/sites/34/2018/05/Position-paper-180417-for-the-EC.pdf.

2. [ATSDR] Agency for Toxic Substances and Disease Registry. 2018. Framework for assessing health impacts of multiple chemicals and other stressors (Update). US Agency for Toxic Substances and Disease Registry. [accessed 2018 July 19]. http://www.atsdr.cdc.gov/interactionprofiles/ip-ga/ipga.pdf.

3. Current EU research activities on combined exposure to multiple chemicals

4. Cumulative risk assessment of the exposure to organophosphorus and carbamate insecticides in the Dutch diet

5. An integrated probabilistic framework for cumulative risk assessment of common mechanism chemicals in food: An example with organophosphorus pesticides

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