Metabolic understanding of disulfide reduction during monoclonal antibody production-Reference-Cited by-同舟云学术

Metabolic understanding of disulfide reduction during monoclonal antibody production

Published:2020-09-30 Issue:22 Volume:104 Page:9655-9669
ISSN:0175-7598
Container-title:Applied Microbiology and Biotechnology
language:en
Short-container-title:Appl Microbiol Biotechnol

Author:

Cura Anthony J.,Xu Xuankuo,Egan Susan,Aron Kathryn^ORCID,Jenkins Lauren,Hageman Tyler,Huang Yunping,Chollangi Srinivas,Borys Michael,Ghose Sanchayita,Li Zheng Jian

Publisher

Springer Science and Business Media LLC

Subject

Applied Microbiology and Biotechnology,General Medicine,Biotechnology

Link

https://link.springer.com/content/pdf/10.1007/s00253-020-10916-1.pdf

Reference37 articles.

1. Anastasiou D, Poulogiannis G, Asara JM, Boxer MB, Jiang JK, Shen M, Bellinger G, Sasaki AT, Locasale JW, Auld DS, Thomas CJ, Vander Heiden MG, Cantley LC (2011) Inhibition of pyruvate kinase M2 by reactive oxygen species contributes to cellular antioxidant responses. Science 334(6060):1278–1283. https://doi.org/10.1126/science.1211485

2. Chen Y, McMillan-Ward E, Kong J, Israels SJ, Gibson SB (2008) Oxidative stress induces autophagic cell death independent of apoptosis in transformed and cancer cells. Cell Death Differ 15(1):171–182. https://doi.org/10.1038/sj.cdd.4402233

3. Chung WK, Russell B, Yang Y, Handlogten M, Hudak S, Cao M, Wang J, Robbins D, Ahuja S, Zhu M (2017) Effects of antibody disulfide bond reduction on purification process performance and final drug substance stability. Biotechnol Bioeng 114(6):1264–1274. https://doi.org/10.1002/bit.26265

4. Evans OB, Stacpoole PW (1982) Prolonged hypolactatemia and increased total pyruvate dehydrogenase activity by dichloroacetate. Biochem Pharmacol 31(7):1295–1300. https://doi.org/10.1016/0006-2952(82)90019-3

5. Ferguson BS, Rogatzki MJ, Goodwin ML, Kane DA, Rightmire Z, Gladden LB (2018) Lactate metabolism: historical context, prior misinterpretations, and current understanding. Eur J Appl Physiol 118(4):691–728. https://doi.org/10.1007/s00421-017-3795-6

Cited by 4 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Raman Spectroscopy for Monitoring Free Sulfhydryl Formation During Monoclonal Antibody Manufacturing;2024

2. New high-throughput screening method for Chinese hamster ovary cell lines expressing low reduced monoclonal antibody levels: application of a system controlling the gas phase over cell lysates in miniature bioreactors and facilitating multiple sample setup;Cytotechnology;2023-07-21

3. New high-throughput screening method for Chinese hamster ovary cell lines expressing low reduced monoclonal antibody levels: Application of a system controlling the gas phase over cell lysates in miniature bioreactors and facilitating multiple sample setup;2023-02-03

4. Untargeted proteomics reveals upregulation of stress response pathways during CHO-based monoclonal antibody manufacturing process leading to disulfide bond reduction;mAbs;2021-01-01