In vitro exploration of potential mechanisms of toxicity of the human hepatotoxic drug fenclozic acid-Reference-Cited by-同舟云学术

In vitro exploration of potential mechanisms of toxicity of the human hepatotoxic drug fenclozic acid

Published:2013-04-23 Issue:8 Volume:87 Page:1569-1579
ISSN:0340-5761
Container-title:Archives of Toxicology
language:en
Short-container-title:Arch Toxicol

Author:

Rodrigues Alison V. M.,Rollison Helen E.,Martin Scott,Sarda Sunil,Schulz-Utermoehl Timothy,Stahl Simone,Gustafsson Frida,Eakins Julie,Kenna J. Gerry,Wilson Ian D.

Publisher

Springer Science and Business Media LLC

Subject

Health, Toxicology and Mutagenesis,Toxicology,General Medicine

Link

http://link.springer.com/content/pdf/10.1007/s00204-013-1056-y.pdf

Reference29 articles.

1. Alcock S (1970) An anti-inflammatory compound: non-toxic to animals but with an adverse action in man. Proc Eur Soc Study Drug Toxic 12:7

2. Argoti D, Liang L, Conteh A, Chen L, Bershas D, Yu CP, Vouros P, Yang E (2005) Cyanide trapping of iminium ion reactive intermediates followed by detection and structure identification using liquid chromatography-tandem mass spectrometry (LC-MS/MS). Chem Res Toxicol 18(10):1537–1544

3. Bauman JN, Kelly JM, Tripathy S, Zhao SX, Lam WW, Kalgutkar AS, Obach RS (2009) Can in vitro metabolism-dependent covalent binding data distinguish hepatotoxic from nonhepatotoxic drugs? An analysis using human hepatocytes and liver s-9 fraction. Chem Res Toxicol 22(2):332–340

4. Boelsterli UA (2002) Xenobiotic acyl glucuronides and acyl CoA thioesters as protein-reactive metabolites with the potential to cause idiosyncratic drug reactions. Curr Drug Metab 3(4):439–450

5. Bradbury A, Powell GM, Curtis CG, Rhodes C (1981) The enhanced biliary secretion of a taurine conjugate in the rat after intraduodenal administration of high doses of fenclozic acid. Xenobiotica 11(10):665–674

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