Acute liver effects, disposition and metabolic fate of [14C]-fenclozic acid following oral administration to normal and bile-cannulated male C57BL/6J mice-Reference-Cited by-同舟云学术

Acute liver effects, disposition and metabolic fate of [14C]-fenclozic acid following oral administration to normal and bile-cannulated male C57BL/6J mice

Published:2016-11-28 Issue:7 Volume:91 Page:2643-2653
ISSN:0340-5761
Container-title:Archives of Toxicology
language:en
Short-container-title:Arch Toxicol

Author:

Pickup Kathryn,Martin Scott,Partridge Elizabeth A.,Jones Huw B.,Wills Jonathan,Schulz-Utermoehl Tim,McCarthy Alan,Rodrigues Alison,Page Chris,Ratcliffe Kerry,Sarda Sunil,Wilson Ian D.

Publisher

Springer Science and Business Media LLC

Subject

Health, Toxicology and Mutagenesis,Toxicology,General Medicine

Link

http://link.springer.com/article/10.1007/s00204-016-1894-5/fulltext.html

Reference15 articles.

1. Alcock S (1970) An anti-inflammatory compound: non-toxic to animals but with an adverse action in man. Proc Eur Soc Study Drug Toxic 12:7

2. Boelsterli UA (2003) Diclofenac-induced liver injury: a paradigm of idiosyncratic drug toxicity. Toxicol Appl Pharmacol 192:307–322

3. Chalmers TM, Kellgren JH, Platt DS (1969a) Evaluation in man of fenclozic acid (I.C.I. 54,450: Myalex), a new anti-inflamatory agent. II. Clinical trial in patients with rheumatoid arthritis. Ann Rheum Dis 28:595–601

4. Chalmers TM, Pohl JE, Platt DS (1969b) Evaluation in man of fenclozic acid (I.C.I. 54,450: Myalex), a new anti-inflammatory agent. I. Serum concentration studies in healthy individuals and in patients with rheumatoid arthritis. Ann Rheum Dis 28:590–594

5. Foulkes DM (1970) The metabolism of C14-ICI 54,450 (myalex) in various species-an in vivo NIH shift. J Pharmacol Exp Ther 172:115–121

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