Antibodies VRC01 and 10E8 Neutralize HIV-1 with High Breadth and Potency Even with Ig-Framework Regions Substantially Reverted to Germline-Reference-Cited by-同舟云学术

Antibodies VRC01 and 10E8 Neutralize HIV-1 with High Breadth and Potency Even with Ig-Framework Regions Substantially Reverted to Germline

Published:2014-01-03 Issue:3 Volume:192 Page:1100-1106
ISSN:0022-1767
Container-title:The Journal of Immunology
language:en
Short-container-title:J.I.

Author:

Georgiev Ivelin S.,Rudicell Rebecca S.,Saunders Kevin O.,Shi Wei,Kirys Tatsiana,McKee Krisha,O’Dell Sijy,Chuang Gwo-Yu,Yang Zhi-Yong,Ofek Gilad,Connors Mark,Mascola John R.,Nabel Gary J.,Kwong Peter D.

Publisher

The American Association of Immunologists

Subject

Immunology,Immunology and Allergy

Reference37 articles.

1. Focused Evolution of HIV-1 Neutralizing Antibodies Revealed by Structures and Deep Sequencing

2. Broad neutralization coverage of HIV by multiple highly potent antibodies

3. Sequence and Structural Convergence of Broad and Potent HIV Antibodies That Mimic CD4 Binding

4. Rational Design of Envelope Identifies Broadly Neutralizing Human Monoclonal Antibodies to HIV-1

5. Broad and Potent Neutralizing Antibodies from an African Donor Reveal a New HIV-1 Vaccine Target

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