Gossypol induces Bax/Bak‐independent activation of apoptosis and cytochrome c release via a conformational change in Bcl‐2-Reference-Cited by-同舟云学术

Gossypol induces Bax/Bak‐independent activation of apoptosis and cytochrome c release via a conformational change in Bcl‐2

Published:2006-08-25 Issue:12 Volume:20 Page:2147-2149
ISSN:0892-6638
Container-title:The FASEB Journal
language:en
Short-container-title:FASEB j.

Author:

Lei Xiaobo¹²,Chen Yingyu¹³,Du Guanhua⁴,Yu Wenyu⁵,Wang Xiaohui¹,Qu Hong⁵,Xia Bin⁵,He Hongping⁶,Mao Jianhua¹,Zong Weixing⁷,Liao Xudong¹,Mehrpour Maryam¹⁸,Hao Xiaojiang⁶,Chen Quan¹,Lei Xiaobo¹²,Chen Yingyu¹³,Du Guanhua⁴,Yu Wenyu⁵,Wang Xiaohui¹,Qu Hong⁵,Xia Bin⁵,He Hongping⁶,Mao Jianhua¹,Zong Weixing⁷,Liao Xudong¹,Mehrpour Maryam¹⁸,Hao Xiaojiang⁶,Chen Quan¹

Affiliation:

1. The Laboratory of Apoptosis and Cancer BiologyThe State Key Laboratory of Biomembrane and Membrane BiotechnologyInstitute of Zoology, Chinese Academy of SciencesBeijingP.R. China

2. Graduate School of the Chinese Academy of SciencesBeijingP.R. China

3. Center for Human Disease GenomicsPeking UniversityBeijingP.R. China

4. Institute of Materia MedicaAcademy Medical Science and Peking Union Medical CollegeBeijingP.R. China

5. College of Life SciencesPeking UniversityBeijingP.R. China

6. The State Key Laboratory of Phytochemistry and Plant Resources in West ChinaKunming Institute of Botany, Chinese Academy of SciencesBeijingP.R. China

7. Abramson Family Cancer Research Institute, Department of Cancer BiologyUniversity of PennsylvaniaPhiladelphiaPennsylvaniaUSA

8. INSERM U‐487, Laboratoire de Cytokines et Immunologie des tumeurs HumainesInstitut Gustave Roussy PR1 and IFR 54VillejuifFrance

Publisher

Wiley

Subject

Genetics,Molecular Biology,Biochemistry,Biotechnology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1096/fj.05-5665fje

Reference39 articles.

1. BH3-only proteins that bind pro-survival Bcl-2 family members fail to induce apoptosis in the absence of Bax and Bak

2. Role of Bcl-2 family proteins in a non-apoptotic programmed cell death dependent on autophagy genes

3. Mitochondrial membrane permeabilisation by Bax/Bak