1. From the Davis Heart and Lung Research Institute (J.A.R., T.T., P.M.L.J., S.V.R.); Division of Cardiovascular Medicine (J.A.R., T.T., P.M.L.J., S.V.R.); Department of Molecular and Cellular Biochemistry (J.A.R., N.S.C., K.E.S., R.G., T.A.M., D.A.D.), and Department of Physiology and Cell Biology (C.D.M., J.D.M., J.E.S., Y.X., B.D.C., P.M.L.J.), The Ohio State University, Columbus, OH.