Affiliation:
1. Departments of Microbiology and Anatomy, New York State Veterinary College, Cornell University, Ithaca, New York 14850
Abstract
Inoculation of susceptible newborn kittens with a large dose of panleukopenia virus caused subclinical infection in 19 of 23 cases. All infected kittens developed severe and prolonged leukopenia. Cell-free virus was present in the blood from 1 to 7 postinoculation days. The virus spread to all organs, regardless of the route of inoculation. The thymus, spleen, mesenteric lymph nodes, and the cerebellum were the most severely infected organs. Kittens responded to virus infection by production of specific antibodies, first detectable in the circulatory system 6 to 8 days after infection. Antibody production preceded recovery from leukopenia by 3 days.
Publisher
American Society for Microbiology
Subject
Infectious Diseases,Immunology,Microbiology,Parasitology
Reference19 articles.
1. Infectious enteritis in the Zoological Gardens;Cockburn A.;Regent's Park Vet. J.,1947
2. Immune carrier state of panleukopenia virus infected cats;Csiza C. K.;Amer. J. Vet. Res.,1971
3. Finney D. J. 1952. Statistical methods in biological assay. Hafner Publishing Co. New York.
4. A virus disease of cats principally characterized by a leucocytosis, enteric lesions and the presence of intranuclear inclusion bodies;Hammon W. D.;J. Exp. Med.,1939
5. Studies on feline distemper;Hindle E.;J. Comp. Pathol. Therap.,1932
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