Polygenic analysis of inflammatory disease variants and effects on microglia in the aging brain
Author:
Funder
National Institutes of Health
Illinois Department of Public Health
Publisher
Springer Science and Business Media LLC
Subject
Cellular and Molecular Neuroscience,Neurology (clinical),Molecular Biology
Link
http://link.springer.com/content/pdf/10.1186/s13024-018-0272-6.pdf
Reference43 articles.
1. Parkes M, Cortes A, van Heel DA, Brown MA. Genetic insights into common pathways and complex relationships among immune-mediated diseases. Nat Rev Genet. 2013;14:661–73.
2. Raj T, Rothamel K, Mostafavi S, Ye C, Lee MN, Replogle JM, et al. Polarization of the effects of autoimmune and neurodegenerative risk alleles in leukocytes. Science. 2014;344:519–23.
3. Bradshaw EM, Chibnik LB, Keenan BT, Ottoboni L, Raj T, Tang A, et al. CD33 Alzheimer’s disease locus: altered monocyte function and amyloid biology. Nat Neurosci. 2013;16:848–50.
4. Huang K, Marcora E, Pimenova A, Narzo AD, Kapoor M, Jin SC, et al. A common haplotype lowers PU.1 expression in myeloid cells and delays onset of Alzheimer's disease. Nat Neurosci. 2017;8;1052-61.
5. Beecham GW, Hamilton K, Naj AC, Martin ER, Huentelman M, Myers AJ, et al. Genome-wide association meta-analysis of Neuropathologic features of Alzheimer’s disease and related dementias. PLoS Genet. 2014;10:e1004606.
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