Identification of dihydropyrazine-glutathione adducts
Author:
Affiliation:
1. Faculty of Pharmaceutical Sciences, Sojo University
2. Institute of Biomaterials and Bioengineering, Tokyo Medical and Dental University
3. Faculty of Pharmaceutical Sciences, Fukuoka University
Publisher
Japanese Society of Toxicology
Subject
Toxicology
Link
https://www.jstage.jst.go.jp/article/jts/40/4/40_495/_pdf
Reference12 articles.
1. Bhattacharya, S.K., Robson, J.S. and Stewart, C.P. (1955): The determination of glutathione in blood and tissues. Biochem. J., 60, 696-702.
2. Ishida, T., Takechi, S. and Yamaguchi, T. (2012): Possible involvement of glutathione balance disruption in dihydropyrazine-induced cytotoxicity on human hepatoma HepG2 cells. J. Toxicol. Sci., 37, 1065-1069.
3. Ishida, T., Yamaguchi, T. and Takechi, S. (2014): The effect of dihydropyrazines on human hepatoma HepG2 cells: a comparative study using 2,3-dihydro-5,6-dimethylpyrazine and 3-hydro-2,2,5,6-tetramethylpyrazine. J. Toxicol. Sci., 39, 601-608.
4. Ito, S., Hirano, T., Sugimoto, A., Kagechika, H., Takechi, S. and Yamaguchi, T. (2010): Latent enamine functionality of 5-Methyl-2,3-dihydropyrazines. Chem. Pharm. Bull., 58, 922-927.
5. Mitchell, J.B. and Russo, A. (1987): The role of glutathione in radiation and drug induced cytotoxicity. Br. J. Cancer (Suppl.), 55, 96-104.
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