Minimising the payload solvent exposed hydrophobic surface area optimises the antibody-drug conjugate properties
Author:
Affiliation:
1. AbbVie Bioresearch Center, 381 Plantation Street, Worcester, Massachusetts 01605, USA
2. AbbVie Inc., 1 North Waukegan Road, North Chicago, IL 60064, USA
Abstract
Funder
Basic Energy Sciences
Publisher
Royal Society of Chemistry (RSC)
Link
http://pubs.rsc.org/en/content/articlepdf/2024/MD/D3MD00540B
Reference28 articles.
1. Antibody–drug conjugates come of age in oncology
2. The discovery and development of brentuximab vedotin for use in relapsed Hodgkin lymphoma and systemic anaplastic large cell lymphoma
3. Synthesis and Biological Evaluation of 2‘-Carbamate-Linked and 2‘-Carbonate-Linked Prodrugs of Paclitaxel: Selective Activation by the Tumor-Associated Protease Plasmin
4. A.Hobson , The Medicinal Chemistry of Glucocorticoid Receptor Modulators, SpringerBriefs in Molecular Science , Springer , Cham , 2023 , ISBN 978–3–031-28732-9, 10.1007/978-3-031-28732-9
5. New Antiarthritic Steroids
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