A study to develop platinum(iv) complex chemistry for peptide disulfide bond formation
Author:
Affiliation:
1. College of Chemistry and Environmental Science
2. Key Laboratory of Analytical Science and Technology of Hebei Province
3. and MOE Key Laboratory of Medicinal Chemistry and Molecular Diagnostics
4. Hebei University
5. Baoding 071002
Abstract
Platinum(iv) complexes with a heterocyclic ligand and an ancillary ligand have been investigated and applied for the formation of disulfide bonds in peptides.
Funder
National Natural Science Foundation of China
Natural Science Foundation of Hebei Province
Publisher
Royal Society of Chemistry (RSC)
Subject
Inorganic Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2020/DT/C9DT04738G
Reference36 articles.
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4. Synthesis, characterisation and potent cytotoxicity of unconventional platinum(iv) complexes with modified lipophilicity
5. Synthesis, characterisation and influence of lipophilicity on cellular accumulation and cytotoxicity of unconventional platinum(iv) prodrugs as potent anticancer agents
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