On-DNA hydroalkylation of <i>N</i>-vinyl heterocycles <i>via</i> photoinduced EDA-complex activation-Reference-Cited by-同舟云学术

On-DNA hydroalkylation of N-vinyl heterocycles via photoinduced EDA-complex activation

Published:2023 Issue:48 Volume:14 Page:14193-14199
ISSN:2041-6520
Container-title:Chemical Science
language:en
Short-container-title:Chem. Sci.

Author:

Sharique Mohammed¹,Matsuo Bianca¹^ORCID,Granados Albert¹^ORCID,Kim Saegun¹,Arshad Mahwish¹,Oh Hyunjung¹,Wu Victoria E.²,Huang Minxue²,Csakai Adam²,Marcaurelle Lisa A.²,Molander Gary A.¹^ORCID

Affiliation:

1. Roy and Diana Vagelos Laboratories, Department of Chemistry, University of Pennsylvania, 231 South 34th Street, Philadelphia, Pennsylvania 19104-6323, USA

2. Encoded Library Technologies/NCE Molecular Discovery, R&D Medicinal Science and Technology, GSK, 200 Cambridge Park Drive, Cambridge, MA 02140, USA

Abstract

The emergence of DNA-encoded library (DEL) technology has provided a considerable advantage to the pharmaceutical industry in the pursuit of discovering novel therapeutic candidates for their drug development initiatives.

Funder

National Institutes of Health

National Institute of General Medical Sciences

National Science Foundation

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2023/SC/D3SC03731B

Reference46 articles.

1. Organic synthesis provides opportunities to transform drug discovery

2. Twenty years on: the impact of fragments on drug discovery

3. Target identification and mechanism of action in chemical biology and drug discovery

4. Exploring biology with small organic molecules

5. Fragment-Based Drug Discovery: Advancing Fragments in the Absence of Crystal Structures

Cited by 2 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Decatungstate‐Photocatalyzed Diastereoselective Dearomative Hydroalkylation of Indoles;European Journal of Organic Chemistry;2024-05-17

2. Access to Benzyl Oxindoles via Electron Donor‐Acceptor Complex Photoactivation Using Thianthrenium Salts and Potassium Carbonate;Advanced Synthesis & Catalysis;2024-05-16