Fragment-Based Drug Discovery: Advancing Fragments in the Absence of Crystal Structures
Author:
Publisher
Elsevier BV
Subject
Clinical Biochemistry,Drug Discovery,Pharmacology,Molecular Biology,Molecular Medicine,Biochemistry
Reference67 articles.
1. Fragment-based drug discovery of potent and selective MKK3/6 inhibitors;Adams;Bioorg. Med. Chem. Lett.,2016
2. Proteome-wide covalent ligand discovery in native biological systems;Backus;Nature,2016
3. SAR by ILOEs: an NMR-based approach to reverse chemical genetics;Becattini;Chemistry,2006
4. Application of off-rate screening in the identification of novel pan-isoform inhibitors of pyruvate dehydrogenase kinase;Brough;J. Med. Chem.,2017
5. Discovery of tricyclic indoles that potently inhibit Mcl-1 using fragment-based methods and structure-based design;Burke;J. Med. Chem.,2015
Cited by 99 articles. 订阅此论文施引文献 订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献
1. Multi-tiered chemical proteomic maps of tryptoline acrylamide–protein interactions in cancer cells;Nature Chemistry;2024-08-13
2. Fast Quantitative Validation of 3D Models of Low-Affinity Protein–Ligand Complexes by STD NMR Spectroscopy;Journal of Medicinal Chemistry;2024-06-07
3. KNIME workflows for applications in medicinal and computational chemistry;Artificial Intelligence Chemistry;2024-06
4. The role of NMR in advancing small molecule drug discovery;Trends in Pharmacological Sciences;2024-04
5. A comparison of human and GPT-4 use of probabilistic phrases in a coordination game;Scientific Reports;2024-03-21
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线，采集、加工和组织学术论文而形成的新型学术文献查询和分析系统，可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容，当前同舟云学术共收录了国内外主流学术期刊6万余种，收集的期刊论文及会议论文总量共计约1.5亿篇，并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询！咨询电话：010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3