Dynamic experiments in flow accelerate reaction network definition in a complex hydrogenation using catalytic static mixers-Reference-Cited by-同舟云学术

Dynamic experiments in flow accelerate reaction network definition in a complex hydrogenation using catalytic static mixers

Published:2024 Issue:1 Volume:9 Page:132-138
ISSN:2058-9883
Container-title:Reaction Chemistry & Engineering
language:en
Short-container-title:React. Chem. Eng.

Author:

Martinuzzi Stefano¹²,Tranninger Markus³^ORCID,Sagmeister Peter¹²^ORCID,Horn Martin³,Williams Jason D.¹²^ORCID,Kappe C. Oliver¹²^ORCID

Affiliation:

1. Center for Continuous Flow Synthesis and Processing (CCFLOW), Research Center Pharmaceutical Engineering GmbH (RCPE), Inffeldgasse 13, 8010 Graz, Austria

2. Institute of Chemistry, NAWI Graz, University of Graz, Heinrichstrasse 28, 8010 Graz, Austria

3. Institute of Automation and Control, Graz University of Technology, Inffeldgasse 21b, 8010 Graz, Austria

Abstract

The combination of transient flow experiments with process analytical technology (PAT) enables the rapid characterization and kinetic modelling of a complex ketone hydrogenation, catalyzed by catalytic static mixers (CSMs).

Funder

Österreichische Forschungsför-derungsgesellschaft

Publisher

Royal Society of Chemistry (RSC)

Subject

Fluid Flow and Transfer Processes,Process Chemistry and Technology,Chemical Engineering (miscellaneous),Chemistry (miscellaneous),Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2024/RE/D3RE00451A

Reference58 articles.

1. Digital methods and tools for chemical equipment and plants

2. Modern advancements in continuous-flow aided kinetic analysis

3. A Brief Introduction to Chemical Reaction Optimization

4. Process analytical technology (PAT): applications to flow processes for active pharmaceutical ingredient (API) development

5. Recommendations for Effective and Defendable Implementation of Quality by Design

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