Single cell-asymmetrical flow field-flow fractionation/ICP-time of flight-mass spectrometry (sc-AF4/ICP-ToF-MS): an efficient alternative for the cleaning and multielemental analysis of individual cells-Reference-Cited by-同舟云学术

Single cell-asymmetrical flow field-flow fractionation/ICP-time of flight-mass spectrometry (sc-AF4/ICP-ToF-MS): an efficient alternative for the cleaning and multielemental analysis of individual cells

Published:2022 Issue:12 Volume:37 Page:2691-2700
ISSN:0267-9477
Container-title:Journal of Analytical Atomic Spectrometry
language:en
Short-container-title:J. Anal. At. Spectrom.

Author:

Chronakis Michail Ioannis¹^ORCID,von der Au Marcus¹^ORCID,Meermann Björn¹^ORCID

Affiliation:

1. Federal Institute for Materials Research and Testing (BAM), Division 1.1 – Inorganic Trace Analysis, Richard-Willstätter-Str. 11, 12489 Berlin, Germany

Abstract

A new approach relying on AF4 for gentle on-line removal of the ionic background from cells during single cell-ICP-ToF-MS analysis was developed. In a first proof-of-concept study the new approach was applied for the analysis of yeast cells.

Funder

Bundesministerium für Wirtschaft und Energie

Publisher

Royal Society of Chemistry (RSC)

Subject

Spectroscopy,Analytical Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2022/JA/D2JA00264G

Reference60 articles.

1. New mass spectrometry technologies contributing towards comprehensive and high throughput omics analyses of single cells

2. Electrophoresis of Hemoglobin in Single Erythrocytes

3. Determination of Calcium Content in Individual Biological Cells by Inductively Coupled Plasma Atomic Emission Spectrometry