Synthesis and biological evaluation of pyrophosphate mimics of thiamine pyrophosphate based on a triazole scaffold-Reference-Cited by-同舟云学术

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Synthesis and biological evaluation of pyrophosphate mimics of thiamine pyrophosphate based on a triazole scaffold

Published:2008 Issue:19 Volume:6 Page:3561
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Erixon Karl M.,Dabalos Chester L.,Leeper Finian J.

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2008/OB/B806580B

Reference36 articles.

1. Current mechanistic understanding of thiamin diphosphate-dependent enzymatic reactions

2. Sixty years of thiamin diphosphate biochemistry

3. How Thiamine Diphosphate Is Activated in Enzymes

4. Elucidation of the Chemistry of Enzyme-Bound Thiamin Diphosphate Prior to Substrate Binding: Defining Internal Equilibria among Tautomeric and Ionization States

5. Snapshot of a key intermediate in enzymatic thiamin catalysis: Crystal structure of the -carbanion of ( , -dihydroxyethyl)-thiamin diphosphate in the active site of transketolase from Saccharomyces cerevisiae

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1. Thiamine analogues featuring amino-oxetanes as potent and selective inhibitors of pyruvate dehydrogenase;Bioorganic & Medicinal Chemistry Letters;2024-01

2. Design of thiamine analogues for inhibition of thiamine diphosphate (ThDP)-dependent enzymes: Systematic investigation through Scaffold-Hopping and C2-Functionalisation;Bioorganic Chemistry;2023-09

3. Inhibition of Thiamine Diphosphate-Dependent Enzymes by Triazole-Based Thiamine Analogues;ACS Medicinal Chemistry Letters;2023-04-11

4. Exploring the structure, function of thiamine pyrophosphate riboswitch, and designing small molecules for antibacterial activity;WIREs RNA;2023-01-02

5. Open-chain thiamine analogues as potent inhibitors of thiamine pyrophosphate (TPP)-dependent enzymes;Organic & Biomolecular Chemistry;2023

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