Covalent drugs targeting histidine – an unexploited opportunity?
Author:
Affiliation:
1. Center for Protein Degradation, Dana-Farber Cancer Institute, 360 Longwood Avenue, Boston, MA, USA
2. Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA, USA
Abstract
Publisher
Royal Society of Chemistry (RSC)
Subject
Organic Chemistry,Drug Discovery,Pharmaceutical Science,Pharmacology,Molecular Medicine,Biochemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2022/MD/D2MD00258B
Reference59 articles.
1. Emerging and Re-Emerging Warheads for Targeted Covalent Inhibitors: Applications in Medicinal Chemistry and Chemical Biology
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