Covalent inhibitors: a rational approach to drug discovery-Reference-Cited by-同舟云学术

Covalent inhibitors: a rational approach to drug discovery

Published:2020 Issue:8 Volume:11 Page:876-884
ISSN:2632-8682
Container-title:RSC Medicinal Chemistry
language:en
Short-container-title:RSC Med. Chem.

Author:

Sutanto Fandi¹²³⁴⁵,Konstantinidou Markella¹²³⁴⁵^ORCID,Dömling Alexander¹²³⁴⁵^ORCID

Affiliation:

1. Department of Pharmacy

2. Group of Drug Design

3. University of Groningen

4. Groningen

5. The Netherlands

Abstract

In this review we provide a brief historic overview of covalent inhibitors and summarize recent advances focusing on developments in the last decade. Applications in challenging targets and future perspectives are also discussed.

Funder

National Institutes of Health

KWF Kankerbestrijding

Lembaga Pengelola Dana Pendidikan

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Drug Discovery,Pharmaceutical Science,Pharmacology,Molecular Medicine,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2020/MD/D0MD00154F

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