Targeted quantitative analysis of anthraquinone derivatives by high-performance liquid chromatography coupled with tandem mass spectrometry to discriminate between crude and processed rhubarb samples
Author:
Affiliation:
1. Key Laboratory of Drug Quality Control and Pharmacovigilance (Ministry of Education)
2. China Pharmaceutical University
3. Nanjing 210009
4. China
5. State Key Laboratory of Natural Medicine
Abstract
A targeted plant metabolomic method has been developed to discriminate crude and processed rhubarb samples based on contents of 13 anthraquinone derivatives.
Funder
National Natural Science Foundation of China
Publisher
Royal Society of Chemistry (RSC)
Subject
General Engineering,General Chemical Engineering,Analytical Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2015/AY/C5AY01067E
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4. Rheinanthrone, a metabolite of sennoside A, triggers macrophage activation to decrease aquaporin-3 expression in the colon, causing the laxative effect of rhubarb extract
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