UHPLC-MS/MS method for the simultaneous quantitation of five anthraquinones and gallic acid in rat plasma after oral administration of prepared rhubarb decoction and its application to a pharmacokinetic study in normal and acute blood stasis rats-Reference-Cited by-同舟云学术

UHPLC-MS/MS method for the simultaneous quantitation of five anthraquinones and gallic acid in rat plasma after oral administration of prepared rhubarb decoction and its application to a pharmacokinetic study in normal and acute blood stasis rats

Published:2017-06 Issue:11 Volume:40 Page:2382-2389
ISSN:1615-9306
Container-title:Journal of Separation Science
language:en
Short-container-title:J. Sep. Sci.

Author:

Zhu Hui¹²³,Liu Xiao¹²³^ORCID,Zhu Ting Ting¹²³,Wang Xiao Li¹²³,Qin Kun Ming⁴,Pei Ke⁵,Cai Bao Chang¹²³⁴

Affiliation:

1. School of Pharmacy; Nanjing University of Chinese Medicine; Nanjing P.R. China

2. Engineering Center of State Ministry of Education for Standardization of Chinese Medicine Processing; Nanjing University of Chinese Medicine; Nanjing P.R. China

3. State Key Laboratory Cultivation Base for TCM Quality and Efficacy; Nanjing University of Chinese Medicine; Nanjing P.R. China

4. Nanjing Haichang Chinese Medicine Group Corporation; Nanjing P.R. China

5. Shanxi University of Traditional Chinese Medicine; Shanxi P.R. China

Funder

Natural Science Foundation of Jiangsu Province

Publisher

Wiley

Subject

Filtration and Separation,Analytical Chemistry

Reference24 articles.

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2. Effect of prepared rhubarb on insulin resistance in patients with pregnancy induced hypertension;Wu;Fitoterapia,2012

3. Comparison of the actions on blood stasis of rhubarb with different prepared methods;Sui;Pharmacol. Clin. Chin. Materia Med.,2012

4. Ultra-performance liquid chromatography-quadrupole\time-of-flight mass spectrometry with multivariate statistical analysis for exploring potential chemical markers to distinguish between raw and processed Rheum palmatum;Wang;Chin. J. Integr. Med.,2003

5. Drug effect comparison of Rhubarb extract by the technology free of heating and the extracts form crude Rhubarb and from prepared Rhubarb;Hu;Chin. Med. Mat.,2003

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