Synthesis and pharmacological effects of the enantiomers of the N-phenethyl analogues of the ortho and para e- and f-oxide-bridged phenylmorphans-Reference-Cited by-同舟云学术

Synthesis and pharmacological effects of the enantiomers of the N-phenethyl analogues of the ortho and para e- and f-oxide-bridged phenylmorphans

Published:2008 Issue:16 Volume:6 Page:2868
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Zezula Josef,Singer Lisa,Przybył Anna K.,Hashimoto Akihiro,Dersch Christina M.,Rothman Richard B.,Deschamps Jeffrey,Lee Yong Sok,Jacobson Arthur E.,Rice Kenner C.

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2008/OB/B803433H

Reference26 articles.

1. Probes for Narcotic Receptor Mediated Phenomena. 34. Synthesis and Structure−Activity Relationships of a Potent μ-Agonist δ-Antagonist and an Exceedingly Potent Antinociceptive in the Enantiomeric C9-Substituted 5-(3-Hydroxyphenyl)-N-phenylethylmorphan Series

2. A Novel Divergent Synthesis of ortho-Hydroxy-E and -F Oxide-Bridged 5-Phenylmorphans

3. Probes for Narcotic Receptor-Mediated Phenomena. 33.1 Construction of a Strained trans-5,6-Ring System by Displacement of a Nitro-Activated Aromatic Fluorine. Synthesis of the Penultimate Oxide-Bridged Phenylmorphans

4. Synthesis of rac-(1R,4aR,9aR)-2-methyl-1,3,4,9a-tetrahydro-2H-1,4a-propanobenzofuro[2,3-c]pyridin-6-ol. An unusual double rearrangement leading to the ortho- and para–f oxide-bridged phenylmorphan isomers

5. Probes for narcotic receptor mediated phenomena. 6. Synthesis of (.+-.)-(1.alpha.,4a.alpha.,9a.beta.)-1,3,4,9a-tetrahydro-2-methyl-2H-1,4a-propanobenzofuro[2,3-c]pyridin-8-ol, an oxide-bridged 5-(3-hydroxyphenyl)morphan

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