Catalytic asymmetric dearomative [4 + 2] annulation of 2-nitrobenzofurans and 5H-thiazol-4-ones: stereoselective construction of dihydrobenzofuran-bridged polycyclic skeletons-Reference-Cited by-同舟云学术

Catalytic asymmetric dearomative [4 + 2] annulation of 2-nitrobenzofurans and 5H-thiazol-4-ones: stereoselective construction of dihydrobenzofuran-bridged polycyclic skeletons

Published:2021 Issue:22 Volume:8 Page:6330-6336
ISSN:2052-4129
Container-title:Organic Chemistry Frontiers
language:en
Short-container-title:Org. Chem. Front.

Author:

Zhao Jian-Qiang¹^ORCID,Zhou Shun¹²,Wang Zhen-Hua¹^ORCID,You Yong¹^ORCID,Chen Shuang³,Liu Xiong-Li³^ORCID,Zhou Ming-Qiang²,Yuan Wei-Cheng¹^ORCID

Affiliation:

1. Institute for Advanced Study, Chengdu University, Chengdu 610106, China

2. National Engineering Research Center of Chiral Drugs, Chengdu Institute of Organic Chemistry, Chinese Academy of Sciences, Chengdu, 610041, China

3. Guizhou Engineering Center for Innovative Traditional Chinese Medicine and Ethnic Medicine, Guizhou University, Guiyang, Guizhou 550025, China

Abstract

An organocatalytic asymmetric dearomative [4 + 2] annulation of 2-nitrobenzofurans and 5H-thiazol-4-ones is developed for the construction of dihydrobenzofuran-bridged polycyclic skeletons with good results.

Funder

National Natural Science Foundation of China

Chengdu University

Sichuan Province Science and Technology Support Program

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2021/QO/D1QO01061A

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1. Biology-Oriented Synthesis