Probes for Narcotic Receptor-Mediated Phenomena. 33.1 Construction of a Strained trans-5,6-Ring System by Displacement of a Nitro-Activated Aromatic Fluorine. Synthesis of the Penultimate Oxide-Bridged Phenylmorphans-Reference-Cited by-同舟云学术

Probes for Narcotic Receptor-Mediated Phenomena. 33.1 Construction of a Strained trans-5,6-Ring System by Displacement of a Nitro-Activated Aromatic Fluorine. Synthesis of the Penultimate Oxide-Bridged Phenylmorphans

Published:2004-07-02 Issue:16 Volume:69 Page:5322-5327
ISSN:0022-3263
Container-title:The Journal of Organic Chemistry
language:en
Short-container-title:J. Org. Chem.

Author:

Hashimoto Akihiro¹,Przybyl Anna K.¹,Linders Joannes T. M.¹,Kodato Shinichi¹,Tian Xinrong¹,Deschamps Jeffrey R.¹,George Clifford¹,Flippen-Anderson Judith L.¹,Jacobson Arthur E.¹,Rice Kenner C.¹

Affiliation:

1. Laboratory of Medicinal Chemistry, National Institute of Diabetes, Digestive and Kidney Diseases, National Institutes of Health, Building 8, Room B1-23, Department of Health and Human Services, Bethesda, Maryland, 20892-0815, and Laboratory for the Structure of Matter, Naval Research Laboratory, Washington, D.C. 20375

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/jo040159k

Reference28 articles.

1. Synthesis of rac-(1R,4aR,9aR)-2-methyl-1,3,4,9a-tetrahydro-2H-1,4a-propanobenzofuro[2,3-c]pyridin-6-ol. An unusual double rearrangement leading to the ortho- and para–f oxide-bridged phenylmorphan isomers

2. Probes for narcotic receptor mediated phenomena. Part 31: Synthesis of rac-(3R,6aS,11aS)-2-methyl-1,3,4,5,6,11a-hexahydro-2H-3,6a-methanobenzofuro[2,3-c]azocine-10-ol, and azocine-8-ol, the ortho-c and the para-c oxide-bridged phenylmorphan isomers

3. 2,5-Bis[(Z)-2-nitrobenzenesulfenylmethylene]-3,6-bis(methylene)-7-oxabicyclo[2.2.1]heptane. A versatile reagent for tandem regioselective Diels-Alder reactions

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