Hypoglycemic effect of <i>Nitraria tangutorum</i> fruit by inhibiting glycosidase and regulating IRS1/PI3K/AKT signalling pathway and its active ingredient identification by UPLC-MS-Reference-Cited by-同舟云学术

Hypoglycemic effect of Nitraria tangutorum fruit by inhibiting glycosidase and regulating IRS1/PI3K/AKT signalling pathway and its active ingredient identification by UPLC-MS

Published:2023 Issue:17 Volume:14 Page:7869-7881
ISSN:2042-6496
Container-title:Food & Function
language:en
Short-container-title:Food Funct.

Author:

Jiang Sirong¹²,Wang Luya¹²,Jia Wenjing¹²,Wu Di¹³,Wu Li¹²,Zhao Xiaohui¹^ORCID,Mei Lijuan¹,Tao Yanduo¹,Yue Huilan¹^ORCID

Affiliation:

1. Key Laboratory of Tibetan Medicine Research, Northwest Institute of Plateau Biology, CAS and Qinghai Provincial Key Laboratory of Tibetan Medicine Research, Qinghai 810008, China

2. University of Chinese Academy of Sciences, Beijing, China

3. Qinghai University, Qinghai, China

Abstract

The hypoglycemic effect of NTB-40 (40% ethanol fraction of Nitraria tangutorum fruit) in type I/II diabetic mice and its underlying mechanism and active ingredient structure were investigated.

Funder

Natural Science Foundation of Qinghai

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

General Medicine,Food Science

Link

http://pubs.rsc.org/en/content/articlepdf/2023/FO/D3FO02495D

Reference42 articles.

1. Polysaccharide from Rosa roxburghii Tratt Fruit Attenuates Hyperglycemia and Hyperlipidemia and Regulates Colon Microbiota in Diabetic db/db Mice

2. International Diabetes Federation , IDF Diabetes Atlas , International Diabetes Federation , Brussels, Belgium , 10th edn, 2021