Effects of bovine lactoferrin on l-DOPA absorption and metabolism in mice
Author:
Affiliation:
1. Wellness & Nutrition Science Institute
2. R&D Division
3. Morinaga Milk Industry Co.
4. Ltd.
5. Zama
6. School of Pharmacy
7. Nihon University
8. Funabashi
9. Japan
Abstract
Bovine lactoferrin (bLF) inhibited catechol-O-methyltransferase (COMT) activity and enhanced concentrations of levodopa (l-DOPA) in mice by co-administration with carbidopa.
Publisher
Royal Society of Chemistry (RSC)
Subject
General Medicine,Food Science
Link
http://pubs.rsc.org/en/content/articlepdf/2018/FO/C7FO01518F
Reference38 articles.
1. Lactoferrin Concentration During Involution of the Bovine Mammary Gland
2. Determination of bovine lactoferrin concentrations in cheese with specific monoclonal antibodies
3. Twenty-five years of research on bovine lactoferrin applications
4. Potent Antibacterial Peptides Generated by Pepsin Digestion of Bovine Lactoferrin
5. Effects of orally administered bovine lactoferrin and lactoperoxidase on influenza virus infection in mice
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1. Bioactive components and mechanisms of Pu-erh tea in improving levodopa metabolism in rats through COMT inhibition;Food & Function;2024
2. Discovery and characterization of naturally occurring potent inhibitors of catechol-O-methyltransferase from herbal medicines;RSC Advances;2021
3. Comparative examination of levodopa pharmacokinetics during simultaneous administration with lactoferrin in healthy subjects and the relationship between lipids and COMT inhibitory activityin vitro;Nutritional Neuroscience;2020-05-22
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