Discovery and characterization of naturally occurring potent inhibitors of catechol-O-methyltransferase from herbal medicines-Reference-Cited by-同舟云学术

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Discovery and characterization of naturally occurring potent inhibitors of catechol-O-methyltransferase from herbal medicines

Published:2021 Issue:17 Volume:11 Page:10385-10392
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Zhao Dong-Fang¹²³⁴,Fan Yu-Fan¹²³⁴,Wang Fang-Yuan¹²³⁴,Hou Fan-Bin¹²³⁴,Gonzalez Frank J.⁵⁶⁷⁸⁹,Li Shi-Yang¹⁰¹¹¹²⁴,Wang Ping¹²³⁴⁵^ORCID,Xia Yang-Liu¹³¹⁴¹⁵⁴^ORCID,Ge Guang-Bo¹²³⁴^ORCID,Yang Ling¹²³⁴

Affiliation:

1. Institute of Interdisciplinary Integrative Medicine Research

2. Shanghai University of Traditional Chinese Medicine

3. Shanghai

4. China

5. Laboratory of Metabolism

6. Center for Cancer Research

7. National Cancer Institute

8. National Institutes of Health

9. Bethesda

10. Analytical Central Laboratory

11. Shenyang Harmony Health Medical Laboratory Co. Ltd

12. Shenyang

13. School of Life Science and Medicine

14. Dalian University of Technology

15. Panjin

Abstract

Discovery and characterization of natural human catechol-O-methyltransferase (hCOMT) inhibitors for Parkinson's disease treatment.

Funder

Natural Science Foundation of Shanghai

National Basic Research Program of China

Fundamental Research Funds for the Central Universities

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2021/RA/D0RA10425F

Reference46 articles.

1. Medicinal Chemistry of Catechol O-Methyltransferase (COMT) Inhibitors and Their Therapeutic Utility

2. Molecular Modeling and Metabolic Studies of The Interaction of Catechol-O-Methyltransferase and a New Nitrocatechol Inhibitor

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