Medicinal Chemistry of Catechol O-Methyltransferase (COMT) Inhibitors and Their Therapeutic Utility-Reference-Cited by-同舟云学术

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Medicinal Chemistry of Catechol O-Methyltransferase (COMT) Inhibitors and Their Therapeutic Utility

Published:2014-09-02 Issue:21 Volume:57 Page:8692-8717
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Kiss László E.¹,Soares-da-Silva Patrício¹²³

Affiliation:

1. Department of Research & Development, BIAL − Portela & Ca, S.A., À Avenida da Siderurgia Nacional, 4745-457 S. Mamede do Coronado, Portugal

2. Department of Pharmacology & Therapeutics, Faculty of Medicine, University of Porto, 4200-319 Porto, Portugal

3. MedInUP − Center for Drug Discovery and Innovative Medicines, University of Porto, 4200-319 Porto, Portugal

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm500572b

Reference179 articles.

1. 3-Methoxy-4-hydroxy-D-mandelic acid, a urinary metabolite of norepinephrine

2. Enzymatic O-Methylation of Epinephrine and Other Catechols

3. O-Methylation of Catechol Amines in Vivo

4. Inhibition of O-Methyltransferase by Catechol and Sensitization to Epinephrine

5. Treatment of Parkinson's Disease

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1. Identification and optimization of nitrophenolic analogues as dopamine metabolic enzyme inhibitors for the treatment of Parkinson’s disease;Bioorganic Chemistry;2024-07

2. Drug Development for Alzheimer’s and Parkinson’s Disease: Where Do We Go Now?;Pharmaceutics;2024-05-24

3. Practical Three-Component Regioselective Synthesis of Drug-Like 3-Aryl(or heteroaryl)-5,6-dihydrobenzo[h]cinnolines as Potential Non-Covalent Multi-Targeting Inhibitors To Combat Neurodegenerative Diseases;ACS Chemical Neuroscience;2024-04-22

4. Fragment-based drug discovery for disorders of the central nervous system: designing better drugs piece by piece;Frontiers in Chemistry;2024-04-18

5. DFT and QSAR study of Catechol-O-methyltransferase (COMT) as inhibitors for Parkinson’s disease treatment;Optical and Quantum Electronics;2024-02-05

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