Molecular Modeling and Metabolic Studies of The Interaction of Catechol-O-Methyltransferase and a New Nitrocatechol Inhibitor-Reference-Cited by-同舟云学术

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Molecular Modeling and Metabolic Studies of The Interaction of Catechol-O-Methyltransferase and a New Nitrocatechol Inhibitor

Published:2003-03-01 Issue:3 Volume:31 Page:250-258
ISSN:0090-9556
Container-title:Drug Metabolism and Disposition
language:en
Short-container-title:Drug Metab Dispos

Author:

Palma P. N.,Bonifácio M. J.,Loureiro A. I.,Wright L. C.,Learmonth D. A.,Soares-da-Silva P.

Publisher

American Society for Pharmacology & Experimental Therapeutics (ASPET)

Subject

Pharmaceutical Science,Pharmacology

Reference38 articles.

1. Synthesis of some novel potent and selective catechol O-methyltransferase inhibitors

2. Kinetics and Crystal Structure of Catechol-O-Methyltransferase Complex with Co-Substrate and a Novel Inhibitor with Potential Therapeutic Application

3. Expression and Characterization of Rat Soluble Catechol-O-methyltransferase Fusion Protein

4. New, Selective Catechol-O-Methyltransferase Inhibitors as Therapeutic Agents in Parkinson’s Disease

5. Catechol-O-methyltransferase-Inhibiting Pyrocatechol Derivatives: Synthesis and Structure-Activity Studies

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4. Unveiling the biopathway for the design of novel COMT inhibitors;Drug Discovery Today;2022-10

5. Discovery of Small Molecules as Membrane-Bound Catechol-O-methyltransferase Inhibitors with Interest in Parkinson’s Disease: Pharmacophore Modeling, Molecular Docking and In Vitro Experimental Validation Studies;Pharmaceuticals;2021-12-31

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