Accessing spiropiperidines from dihydropyridones through tandem triflation–allylation and ring-closing metathesis (RCM)-Reference-Cited by-同舟云学术

Accessing spiropiperidines from dihydropyridones through tandem triflation–allylation and ring-closing metathesis (RCM)

Published:2023 Issue:25 Volume:21 Page:5245-5253
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Gantasala Naresh¹,Fournet Corentin²,Le Roch Myriam²,Lalli Claudia²^ORCID,Pabbaraja Srihari¹³^ORCID,Gouault Nicolas²^ORCID

Affiliation:

1. CSIR-Indian Institute of Chemical Technology, Uppal Road, Tarnaka, Hyderabad, 500007, TS, India

2. Univ. Rennes, CNRS, ISCR (Institut des Sciences Chimiques de Rennes), UMR 6226, F-35000 Rennes, France

3. Academy of Scientific and Innovative Research (AcSIR), Ghaziabad-201002, India

Abstract

We report an approach to build 2-spiropiperidine moieties starting from dihydropyridones through a tandem triflation–allylation reaction followed by ring-closing metathesis and then Pd-catalyzed functionalization.

Funder

Université de Rennes 1

Council of Scientific and Industrial Research, India

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2023/OB/D3OB00545C

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1. Escape from Flatland: Increasing Saturation as an Approach to Improving Clinical Success

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5. Fsp3-rich and diverse fragments inspired by natural products as a collection to enhance fragment-based drug discovery

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