Selected applications of Meldrum's acid – a tutorial-Reference-Cited by-同舟云学术

Selected applications of Meldrum's acid – a tutorial

Published:2021 Issue:23 Volume:19 Page:5014-5027
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Brosge Felix¹²³⁴^ORCID,Singh Pardeep¹²³⁴,Almqvist Fredrik¹²³⁴,Bolm Carsten¹²³⁴^ORCID

Affiliation:

1. Institute of Organic Chemistry

2. RWTH Aachen University

3. 52074 Aachen

4. Germany

Abstract

The overview describes synthetic routes towards substituted Meldrum's acids and its recent applications to inspire lab veterans and chemistry younglings.

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2021/OB/D1OB00395J

Reference65 articles.

1. LIV.—A β-lactonic acid from acetone and malonic acid

2. The Structure of Meldrum's Supposed β-Lactonic Acid

3. Rationale for the Acidity of Meldrum's Acid. Consistent Relation of C−H Acidities to the Properties of Localized Reactive Orbital

4. New Insight on the Origin of the Unusual Acidity of Meldrum's Acid from ab Initio and Combined QM/MM Simulation Study

5. One hundred years of Meldrum’s acid: advances in the synthesis of pyridine and pyrimidine derivatives

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