5-Heptadecylresorcinol attenuates oxidative damage and mitochondria-mediated apoptosis through activation of the SIRT3/FOXO3a signaling pathway in neurocytes-Reference-Cited by-同舟云学术

5-Heptadecylresorcinol attenuates oxidative damage and mitochondria-mediated apoptosis through activation of the SIRT3/FOXO3a signaling pathway in neurocytes

Published:2020 Issue:3 Volume:11 Page:2535-2542
ISSN:2042-6496
Container-title:Food & Function
language:en
Short-container-title:Food Funct.

Author:

Liu Jie¹²³⁴,Wang Yu¹²³⁴,Hao Yiming¹²³⁴,Wang Zongwei¹²³⁴,Yang Zihui¹²³⁴,Wang Ziyuan¹²³⁴,Wang Jing¹²³⁴⁵^ORCID

Affiliation:

1. China-Canada Joint Lab of Food Nutrition and Health (Beijing)

2. Beijing Technology & Business University (BTBU)

3. Beijing 100048

4. China

5. Beijing Advanced Innovation Center for Food Nutrition and Human Health

Abstract

5-Heptadecylresorcinol (AR-C17) is a main component of the alkylresorcinols (ARs), and has been widely used as a biomarker for whole grain rye consumption. Our study suggested AR-C17 attenuated neurocytes oxidative damage and apoptosis through SIRT3/FOXO3a signaling pathway.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

General Medicine,Food Science

Link

http://pubs.rsc.org/en/content/articlepdf/2020/FO/C9FO03028J

Reference28 articles.

1. Icariin protects rotenone-induced neurotoxicity through induction of SIRT3

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3. Effectiveness of the Mediterranean Diet: Can It Help Delay or Prevent Alzheimer's Disease?