A general, simple and green process to access pyrrolo[2,1-a]isoquinolines using a KI/TBHP catalytic system

Author:

Huang Huan-Ming123,Huang Fang4567,Li Yu-Jin123,Jia Jian-Hong123,Ye Qing123,Han Liang123,Gao Jian-Rong123

Affiliation:

1. State Key Laboratory Breeding Base of Green Chemistry-Synthesis Technology

2. Zhejiang University of Technology

3. Hangzhou, P. R. China

4. Department of Pharmacology

5. School of Pharmaceutical Sciences

6. Southern Medical University

7. Guangzhou 510515, China

Abstract

A novel KI/TBHP-catalyzed 1,3-dipolar cycloaddition/oxidation/aromatization cascade reaction provided a general, efficient and green access to biologically important pyrrolo[2,1-a]isoquinolines.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

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