Investigation of miscellaneous hERG inhibition in large diverse compound collection using automated patch-clamp assay-Reference-Cited by-同舟云学术

Investigation of miscellaneous hERG inhibition in large diverse compound collection using automated patch-clamp assay

Published:2016-01 Issue:1 Volume:37 Page:111-123
ISSN:1671-4083
Container-title:Acta Pharmacologica Sinica
language:en
Short-container-title:Acta Pharmacol Sin

Author:

Yu Hai-bo,Zou Bei-yan,Wang Xiao-liang,Li Min

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology (medical),Pharmacology,General Medicine

Link

http://www.nature.com/articles/aps2015143.pdf

Reference42 articles.

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3. Zhang KP, Yang BF, Li BX . Translational toxicology and rescue strategies of the hERG channel dysfunction: biochemical and molecular mechanistic aspects. Acta Pharmacol Sin 2014; 35: 1473–84.

4. Babcock JJ, Li M . hERG channel function: beyond long QT. Acta Pharmacol Sin 2013; 34: 329–35.

5. ICH S7B. Guideline on safety pharmacology studies for assessing the potential for delayed ventricular repolarization (QT interval prolongation) by human pharmaceuticals 2005.

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