Translational toxicology and rescue strategies of the hERG channel dysfunction: biochemical and molecular mechanistic aspects
Author:
Publisher
Springer Science and Business Media LLC
Subject
Pharmacology (medical),Pharmacology,General Medicine
Link
http://www.nature.com/articles/aps2014101.pdf
Reference97 articles.
1. Vandenberg JI, Perry MD, Perrin MJ, Mann SA, Ke Y, Hill AP . hERG K+ channels: structure, function, and clinical significance. Physiol Rev 2012; 92: 1393–478.
2. Sanguinetii MC, Tristani-Firouzi M . hERG potassium channels and cardiac arrhythmia. Nature 2006; 440: 463–9.
3. Babcock JJ, Li M . hERG channel function: beyond long QT. Acta Pharmacol Sin 2013; 34: 329–35.
4. Warmke JW, Ganetzky B . A family of potassium channels genes related to eag in Drosophila and mamals. Proc Natl Acad Sci U S A 1994; 91: 3438–43.
5. Sanguinetti MC, Jiang CG, Curran ME, Keating MT . A mechanistic link between an inherited and an acquired cardiac arrhythmia: HERG encodes the Ikr potassium channel. Cell 1995; 81: 299–307.
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