Inhibition of poly-LacNAc biosynthesis with release of CMP-Neu5Ac feedback inhibition increases the sialylation of recombinant EPO produced in CHO cells-Reference-Cited by-同舟云学术

Inhibition of poly-LacNAc biosynthesis with release of CMP-Neu5Ac feedback inhibition increases the sialylation of recombinant EPO produced in CHO cells

Published:2018-05-08 Issue:1 Volume:8 Page:
ISSN:2045-2322
Container-title:Scientific Reports
language:en
Short-container-title:Sci Rep

Author:

Lee Chung-Geun,Oh Myung Jin,Park Seung-Yeol,An Hyun Joo,Kim Jung Hoe

Publisher

Springer Science and Business Media LLC

Subject

Multidisciplinary

Link

http://www.nature.com/articles/s41598-018-25580-9.pdf

Reference37 articles.

1. Varki, A. Biological roles of oligosaccharides: all of the theories are correct. Glycobiology 3, 97–130 (1993).

2. Goochee, C. F., Gramer, M. J., Andersen, D. C., Bahr, J. B. & Rasmussen, J. R. The oligosaccharides of glycoproteins: bioprocess factors affecting oligosaccharide structure and their effect on glycoprotein properties. Biotechnology (N Y) 9, 1347–1355 (1991).

3. Jenkins, N. & Curling, E. M. Glycosylation of recombinant proteins: problems and prospects. Enzyme Microb Technol 16, 354–364 (1994).

4. Walsh, G. & Jefferis, R. Post-translational modifications in the context of therapeutic proteins. Nat Biotechnol 24, 1241–1252, https://doi.org/10.1038/nbt1252 (2006).

5. Fukuda, M. N., Sasaki, H., Lopez, L. & Fukuda, M. Survival of recombinant erythropoietin in the circulation: the role of carbohydrates. Blood 73, 84–89 (1989).

Cited by 8 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Recombinant Human CD19 in CHO-K1 Cells: Glycosylation Patterns as a Quality Attribute of High Yield Processes;International Journal of Molecular Sciences;2023-06-30

2. Enzymatic removal of sialic acid enables iCIEF stability monitoring of charge variants of a highly sialylated bispecific antibody;ELECTROPHORESIS;2022-04-27

3. Rapid Antibody in CHO Cells Via RNA and CGE-LIF N-Glycomics;Glycosylation;2021-10-06

4. Big-Data Glycomics: Tools to Connect Glycan Biosynthesis to Extracellular Communication;Trends in Biochemical Sciences;2021-04

5. Glycoengineering Chinese hamster ovary cells: a short history;Biochemical Society Transactions;2021-03-11