Dynamics and ligand-induced conformational changes in human prolyl oligopeptidase analyzed by hydrogen/deuterium exchange mass spectrometry
Author:
Publisher
Springer Science and Business Media LLC
Subject
Multidisciplinary
Link
http://www.nature.com/articles/s41598-017-02550-1.pdf
Reference36 articles.
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2. D’Agostino, G. et al. Prolyl endopeptidase-deficient mice have reduced synaptic spine density in the CA1 region of the hippocampus, impaired LTP, and spatial learning and memory. Cereb Cortex 23, 2007–2014, doi: 10.1093/cercor/bhs199 (2013).
3. Hofling, C. et al. Deficiency of prolyl oligopeptidase in mice disturbs synaptic plasticity and reduces anxiety-like behaviour, body weight, and brain volume. Eur Neuropsychopharmacol 26, 1048–1061, doi: 10.1016/j.euroneuro.2016.02.015 (2016).
4. Di Daniel, E. et al. Prolyl oligopeptidase binds to GAP-43 and functions without its peptidase activity. Mol Cell Neurosci 41, 373–382, doi: 10.1016/j.mcn.2009.03.003 (2009).
5. Brandt, I. et al. Prolyl oligopeptidase stimulates the aggregation of alpha-synuclein. Peptides 29, 1472–1478, doi: 10.1016/j.peptides.2008.05.005 (2008).
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