Molecular Mechanism for Conformational Dynamics of Ras·GTP Elucidated from In-Situ Structural Transition in Crystal-Reference-Cited by-同舟云学术

Molecular Mechanism for Conformational Dynamics of Ras·GTP Elucidated from In-Situ Structural Transition in Crystal

Published:2016-05 Issue:1 Volume:6 Page:
ISSN:2045-2322
Container-title:Scientific Reports
language:en
Short-container-title:Sci Rep

Author:

Matsumoto Shigeyuki,Miyano Nao,Baba Seiki,Liao Jingling,Kawamura Takashi,Tsuda Chiemi,Takeda Azusa,Yamamoto Masaki,Kumasaka Takashi,Kataoka Tohru,Shima Fumi

Publisher

Springer Science and Business Media LLC

Subject

Multidisciplinary

Link

http://www.nature.com/articles/srep25931.pdf

Reference46 articles.

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2. Huang, L., Hofer, F., Martin, G. S. & Kim, S. H. Structural basis for the interaction of Ras with RalGDS. Nat Struct Biol 5, 422–6 (1998).

3. Nassar, N. et al. The 2.2 A crystal structure of the Ras-binding domain of the serine/threonine kinase c-Raf1 in complex with Rap1A and a GTP analogue. Nature 375, 554–60 (1995).

4. Pacold, M. E. et al. Crystal structure and functional analysis of Ras binding to its effector phosphoinositide 3-kinase gamma. Cell 103, 931–43 (2000).

5. Vetter, I. R. & Wittinghofer, A. The guanine nucleotide-binding switch in three dimensions. Science 294, 1299–304 (2001).

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